Through three product generations, and more than 20 years of patient satisfaction, Stretta has come a long way.

• 82+ million covered lives (up from 32m in 2018)
• 35,000 procedures performed
• 15 year follow up data(1)

How does Minimally Invasive Stretta Therapy Compare to other antireflux procedures?
“Among the clinically available antireflux procedures, Stretta is the safest, least invasive, most well-tolerated, and easiest to perform.”(2)
And all without medication, implants, fibrosis, or surgical anatomy change.  The clinicals speak for themselves.

Stretta v PPIs for NERD
“The symptom score improvement was significantly superior in the Stretta group compared to the PPI group (6.3±3.4 vs 8.5±4.1, p =.03). LES pressure increased significantly in the Stretta group compared to the PPI group (14.2±4.4 mm Hg vs 10.0±4.0 mm Hg, P<.01). Although both interventions improved 24-hour pH parameters, including number of acid episodes (p = .27), acid exposure time (p = .39), and DeMeester score (p = .28), no difference was found between the 2 groups. Complete PPI cessation rate (82% vs 52%, p=.03) as well as satisfaction rate (89% vs 57%, p =.02) was much higher in [the] Stretta group than those in the PPI group. The Stretta procedure was safe and effective in the short term for the management of NERD. The Stretta procedure resulted in higher LES pressure and achieved better improvement of symptom control and PPI cessation than did PPI…”(3)

Stretta v Toupet Fundoplication for GERD 
“Taken together, we have found that SFR can significantly improve the esophageal pH and pressure in GERD patients without increasing the risk of poor prognosis and are equally effective and safe as compared to TF. Therefore, SFR could be an option for the treatment of refractory GERD.”(4)

Stretta v Toupet Fundoplication for GERD with Extra-Esophageal Symptoms
“Ninety patients were available at the 3-year follow-up. The total of the frequency and severity scores for every symptom improved in both groups (p < 0.05). Improvement in symptom scores of cough, sputum, and wheezing did not achieve statistical significance between the two groups (p > 0.05). However, the score for globus hystericus was different between the Stretta group and the LTF group (4.9 ± 2.24 vs 3.2 ± 2.63, p < 0.05). After the Stretta procedure and LTF treatment, 29 and 33 patients in each group achieved PPI therapy independence (61.7% vs 64.7%, p = 0.835)…The Stretta procedure and LTF were both safe and effective for the control of GERD-related extra-esophageal symptoms and the reduction of PPI use.” (5)

Stretta v TIF
“In terms of short-term reduction of the HRQL score and heartburn score in patients with GERD, TIF and Stretta may be comparable to each other, and both may be more effective than PPIs. TIF may increase the LES pressure in comparison with Stretta and PPIs. PPIs may reduce the percentage of time pH <4.0 when compared with TIF.”(6)

Stretta v ARMS
“The clinical efficacies of ARMS and SRF 6 months post-operation were equivalent. The
results showed that both ARMS and SRF treatment were acceptable for patients with GEFV grades II and III, while ARMS should be selected for patients with GEFV grade IV.”(7)

Learn More about Stretta Generation 3
Interested in learning more about Stretta, its clinical efficacy, or insurance coverage? Contact us at 800.352.1512 or email us at contact@restech.com.

With all we’ve achieved since the product was first introduced we can’t wait to see what the next twenty years will bring  Thank you for your interest and support.

References:
1. Reymunde, Alvaro MD; Santiago, Nilda MD. Fifteen Plus Years After Stretta Antireflux Endoscopy Procedure: Quality of Life and PPI Requirements: 820. Am J Gastroenterol 112:p S459-S460, October 2017.
2. Triadafilopoulos G. Endoscopic Non-ablative Radiofrequency Treatment (Stretta) for Gastroesophageal Reflux Disease (GERD). Curr Gastroenterol Rep. Published online February 23, 2024.
3. He S, Xu F, Xiong X, et al. Stretta procedure versus proton pump inhibitors for the treatment of nonerosive reflux disease: A 6-month follow-up. Medicine (Baltimore). 2020;99(3):e18610.
4. Ma L, Li T, Liu G, Wang J, Yin Z, Kang J. Stretta radiofrequency treatment vs Toupet fundoplication for gastroesophageal reflux disease: a comparative study. BMC Gastroenterol. 2020;20(1):162. Published 2020 May 27.
5.  Yan C, Liang WT, Wang ZG, et al. Comparison of Stretta procedure and toupet fundoplication for gastroesophageal reflux disease-related extra-esophageal symptoms. World J Gastroenterol. 2015;21(45):12882-12887.
6. Xie P, Yan J, Ye L, et al. Efficacy of different endoscopic treatments in patients with gastroesophageal reflux disease: a systematic review and network meta-analysis. Surg Endosc. 2021;35(4):1500-1510.
7. Sui X, Gao X, Zhang L, et al. Clinical efficacy of endoscopic antireflux mucosectomy vs. Stretta radiofrequency in the treatment of gastroesophageal reflux disease: a retrospective, single-center cohort study. Ann Transl Med. 2022;10(12):660.